Spain’s personalized nutrition pact addresses cognitive health

Announced earlier this week, the HEALTH4BRAIN project will look at personalizing diets using a nutrigenetic test that will aid in the design of personalized and functional foods.

The hope is that personalized counseling will be offered based on an individual’s genetic profile, with tailor-made foods produced that maintain cognitive function and the health of the population.

Commenting on the three-year project, Madrid-based Natac Biotech said he would, “Aim to make the most of ‘omics’ technologies and knowledge in the application of precision nutrition to improve the effectiveness of nutritional strategies and products to optimize cognitive abilities.”

Further details on the project will allow Natac Biotech to take the lead in the production of food-based products created according to an individual’s genetic profile.

The effect of the product on the brain will be the subject of nutrigenomic studies. in vitroCarried out by the IMDEA Institute to determine its mechanism of action, and in vivoTo validate its effectiveness.

Financial details of the project were provided by its funders, the Spanish Ministry of Science and Innovation, which has allocated a budget of around 540,000 €.

Another breakdown reveals that around € 194,000 has been set aside as a grant and around € 285,000 in business loans.

The burden of cognitive decline

“It is estimated that cognitive disorders in Spain affect around 18.5% of the population over 65, with women having significantly higher prevalence rates than the male population”,Highlights IMDEA Food.

“This rises to 45.3% in the case of the population over 85 years old. With the increase in life expectancy, cognitive deterioration is a public health problem that increases over the years as more than 35 million patients with Alzheimer’s dementia are currently diagnosed, and it is expected to that by 2050 they will be overcome even the 135 million.

The details of the collaboration coincide with a series of personalized nutrition news that shines a light on the momentum this field has generated as the sports nutrition, healthy aging and nutricosmetics industries watch it with interest.

This week alone, the University of Toronto provided details of a new studyWhich identifies a genetic variation that regulates iron metabolism, which can improve endurance performance in athletes.

The results could help explain the association between genetic variation and elite athletes in many sports and may help competitive athletes fine-tune their iron intake to improve performance.

Further evidence for the influence of genes on nutrient efficiency has come in the form of a PLOS Genetics study, Who attempted to identify specific genes that could dictate whether fish oil supplements would benefit or harm a person’s heart health.

The US-based team found that the success of fish oil supplementation depended on the genotype with a specific genetic history responsible for lowering triglycerides after supplementation.

Conversely, an altered genotype can increase triglyceride levels after taking a fish oil supplement.

EU customization support

EU help to advance personalized product development came in October last year as therapeutic microbiome company MyBiotics Pharma received € 2 M ($ 2.3 M) in fundingBy the European Union (EU) to develop technology capable of delivering personalized probiotics to fight intestinal disease.

The prize, awarded as part of the European Horizon 2020 program, was also awarded by the company for tailoring probiotic interventions to recover damaged gut microbiota and to develop multi-strain libraries in preparation.

In 2019, the Quadram Institute Bioscience (QIB) secured a share of a European funding pot of 56.4 million euros to work with nutrition start-ups that include a digital platform offering services of personalized nutrition in Europe.

British company QIB collaborated on the EIT Food QUISPER project, an initiative designed to organize and provide consumers with personalized nutritional advice.

Work started with programming a full-fledged digital online service from a pre-beta version (Quisper Server Platform, QSP).

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